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عمومی::
وابستگی سطح اکسیژن خون
The components of the original Model remain in place (in bold text).
The popular blood oxygenation level dependent (BOLD) contrast, used to measure brain activity, is based on the fact that hemoglobin has different magnetic properties depending on its state of oxygenation: oxyhemoglobin is diamagnetic, while deoxyhemoglobin is paramagnetic, and paramagnetic substances distort the surrounding magnetic field more.
This in turn, leads to a localized increase in BOLD signal intensity in that brain region, which is measured using high-field magnetic resonance scanners (Huettel, Song, & McCarthy, 2004).
Thus, the BOLD signal represents an indirect and correlative measure of local neuronal activity.
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